产品名	钙离子载体A23187
别名	离子载体(钙镁盐混合物);钙离子载体 A23187;钙离子载体A23187(钙镁混合盐);卡西霉素;离子载体;抗生素 A 23187;钙离子载体
英文名	Calcium Ionophore A23187
CAS号	52665-69-7
分子式	C29H37N3O6
分子量	523.620588064194
EINECS编号	258-084-1
MDL号

CAS：52665-69-7
分子式C29H37N3O6  分子量523.62
应用范围： 
高选择性钙离子载体增强对 NMDA 非使君子氨酸的响应。在细胞培养中，通过钙调素依赖结构型一氧化氮合酶刺激一氧化氮的生成。
与二价阳离子形成稳定络合物的移动离子载体。用于增加细胞内Ca 2+水平。还充当氧化磷酸化的解偶联剂和线粒体ATPase活性的抑制剂
溶解性： Soluble in water (Partly miscible), DMSO (1 mg/ml), and DMF (10 mg/ml).
如果有可能，您尽量在同一天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的
密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时

保存：-20℃避光保存

A23187 is an ionophore, highly selective for Ca2+, that allows for divalent cations to move across the membranes which are usually
impermeable to them. The compound was originally isolated from Streptomyces chartreusensis for use as an antibiotic but has been
shown to have weak in vitro antimicrobial activity against fungi and gram positive bacteria. Because of its ability to increase intracellular
calcium levels of intact cells, it is used in studies of intracellular Ca2+ mediated events. A23187 has been observed to induce cell activation,
differentiation or proliferation. In vitro experimentation has shown A23187 to boost ROS generation and platelet fragmentation